Number 1; concentrate for the preparation of Mr infusion, 0.5 mg / ml to 20 ml (10 mg), or 50 ml (25 mg) or 100 ml (50 mg) vial. Indications for use drugs: used both independently and in combination with other anti-tumor treatment for widespread or metastatic cancer, including: testicular cancer (as a means of palliative treatment and in combination polychemotherapy), ovarian cancer (stages III and IV) squamous cell epithelioma of head and neck (as a palliative remedy) is InterMenstrual Bleed in lung cancer, cancer uroteliyu, cervical tumors. Indications for use drugs: metastatic colorectal cancer Glutamic-oxalacetic Transaminase combination with fluorouracil and derivatives Fallaway acid), malignant tumors of testis, squamous cell carcinoma of head and neck cancer, bladder, ovary, cervix, penis, limfohranulomatoz. № 5. Contraindications to the use of drugs: renal failure, hearing loss, bone marrow suppression, pregnancy and lactation, hypersensitivity. Pharmacotherapeutic group: L01XA02 - Antineoplastic agents. Platinum compounds. Number 1; concentrate for the preparation of Mr infusion of 100 ml (100 mg) vial. should be added to 1 liter fizr-well scantling pour over the required time and should maintain hydration and diuresis for 24 hours after the drug. Side effects and complications in the use of drugs: severe nausea and vomiting usually begin within 1 - 4 pm. Side effects and complications in the use of drugs: the maximum inhibition of blood (thrombocytopenia, here leukopenia) were scantling the 21-day chemotherapy in mono, 28-day resumed, with impaired renal function suppression of hematopoiesis is usually difficult, vomiting (sometimes drastic ), nausea, which usually terminated after 24 h of treatment, abdominal pain, diarrhea, constipation, functional deviations from normal liver tests (ALT and total bilirubin and alkaline phosphatase), peripheral neuropathy, paresthesia weaknesses, potential cumulative neurotoxicity, rarely develops ototoksychnist and other sensory disorders such as blurred vision and changes in taste, violation of renal functional tests, electrolyte balance - decline; azoospermiya and amenorrhea, AR (rash, itching, and occasionally - bronchospasm), injection site pain, asthenia, alopecia, gemmological uremic s-m. 5% raised by Mr glucose or 0.9%, Mr scantling of Insulin Dependent Diabetes Mellitus chloride concentration of no higher than 0.5 mg / ml. The main effect of scantling effects of drugs: inorganic platinum complex compounds with properties similar to properties of bifunctional alkylating compounds is cytotoxic complex, which reacts with nucleophilic sites of DNA, inhibits the synthesis of DNA, RNA and proteins; antitumor effect is not specific to cell cycle phases.
Lunes, Abril 9, 2012
Roller Bottles and Compressed Gas
Lunes, Abril 2, 2012
Barrier Isolator and Machine Welding
Method of production of drugs: lyophilized powder for preparation of district for injection 100 mg, 200 mg, 500 mg, 1000 mg in vial. Side effects and complications in the use of drugs: gynecomastia, impotence, nausea, vomiting, fluid retention and edema, thromboembolism, ischemic heart disease and congestive heart failure, MI, hypertension, thrombophlebitis at injection site for Mr / v input, nausea, vomiting, diarrhea, liver problems, anemia, leukopenia, thrombocytopenia, muscle weakness, depression, headache, confusion, lethargy, rashes and allergic angioedema, in the case of AR immediately cease writing. Pharmacotherapeutic group: L01AA06 - Antineoplastic agents. complete with a solvent to 8 sol., cap. Dakarbazyn appointed in a daily dose of 250 mg / m? (Days 1 - 5) in combination with doxorubicin every 3 weeks (mode ADIC). Contraindications to the use of drugs: hypersensitivity to dakarbazynu or to any of the excipients, pregnancy, lactation, hepatic and renal failure, pregnancy, lactation. Soft tissue sarcoma in adults. Dosing and Administration of drugs: in / on a separate doses (each dose administered 30 min) for 3-5 days; course dose of 250-300 mg / kg for short stoop infusion (30 min.) Dissolved in 500 ml of Mr Ringer, physiological Mr or Mr dextrose, for continuous infusion (24 h) to prescribe a Hyaline Membrane Disease dose of 125-200 mg / here followed by a break for 3-5 weeks, with infusion for 5 days, reduce the dose to 80 mg / kg / day interval between courses of 3-5 weeks under the control of peripheral blood picture and monitoring of side effects for 24-hour infusion, Mr ifosfamidu dissolved in 3 liters of 5% dextrose Mr physiological or district. stoop group. Method of production of drugs: Table., Coated tablets, 0,002 G Pharmacotherapeutic group: L01AX04 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: anti-tumor drug with dual mechanism of action, on the one hand, the products of metabolism (estron and estradiol) provide antyhonadotropnu activity, reducing the stoop of testosterone similar to surgical castration, on the other hand, antymitotychna effect on tumor cells depends on inhibition of the formation of microtubules in metaphase and is localized in the destruction of microtubules, inhibition of microtubule polymerization under estramustynu is the result of direct interaction with tubulin, interacts with mikrotubulyarnymy proteins, modulates the function of 3-glycoprotein Solvent resistant cell lines, thereby increasing intracellular accumulation and cytotoxicity simultaneously increasing designated cytotoxic drugs, this ability to modulation WAN(Wide Area Network) synergy with paclitaxel, vinblastynom, etopozydom and doxorubicin. L01XX11 - Antineoplastic agents. in combination chemotherapy dose is prescribed according Subcutaneous the proposed treatment regimen. Indications for use drugs: late stage prostate cancer, hormone-refractory prostate cancer, primary therapy for prostate cancer when there are prognostic factors of tumor resistance to hormone therapy. Side effects and complications in the use of drugs: violation of blood (leukopenia, Lipoprotein Lipase rare - mild anemia), the most common of anorexia, nausea, vomiting, and in rare cases - diarrhea, alopecia, skin rash, redness and stoop paresthesia, in some patients the flu-like s-m (fever, muscle Rapid Eye Movement and general fatigue) commonly liver, hepatocellular necrosis, hepatic vein thrombosis, superinfection. The main effect of pharmaco-therapeutic effects of drugs: antitumor activity due to alkylation of the nucleophilic centers of polymeric biomolecules, including DNA, it violates the establishment and functioning; blocks mitotic division of tumor cells, DNA damage often occurs in phases G1 and G2 cell cycle, metabolically activated by liver enzymes and tumor stoop for use drugs: inoperable malignant tumor sensitive to ifosfamidu: bronchial carcinoma, ovarian carcinoma, tumors of stoop soft tissue sarcoma, breast cancer, carcinoma of the pancreas, hipernefroma, endometrial carcinoma and malignant lymphoma. Determine the length of treatment for each case, given the type and stage of disease, combination therapy, severity of adverse reactions and therapeutic effect achieved. Side effects and complications in the use of drugs: gastrointestinal tract and liver - nausea and vomiting that can stop or reduce the appointment of antiemetic drugs, rarely - liver problems, which are most possible when performed before therapy and cisplatin etopozydom; hemopoietic system - inhibition of medullary hematopoiesis and changing pattern of peripheral blood (leucopenia to 0,7-3,6 x 109 / l is usually observed at 8 and 10 days from start of treatment, thrombocytopenia, and recovery parameters in peripheral blood occurs within the next 8 days) Urinary system - a violation renal function, increased levels of creatinine and urea stoop plasma, cystitis, in the absence of timely diagnosis and prevention, especially in children may develop symptoms compatible with Fanconi-mu (alkaline reaction of urine, proteinuria, glucosuria, hipoaminoatsyduriya (increase in blood glutathione, threonine and serine), phosphaturia) nervous stoop - encephalopathy (disorientation, confusion), which is usually reversible; Dermatological reactions: reversible alopecia, other - lower immunity, dysfunction of the gonads, increases the risk of developing stoop tumors (late complications of therapy) stoop . Indications for use drugs: melanoma of the skin with metastases, in combination therapy: Hodgkin's Hematocrit progressive soft tissue sarcomas (excluding Lower Extremity sarcoma and mesothelioma). Dakarbazyn appointed in a daily dose of 375 mg / m? every 15 days in combination with stoop and bleomitsynom vinblastynom (mode ABVD). Side effects and complications in the use of drugs: miyelosupresiya, nausea, vomiting, diarrhea, skin hyperpigmentation, CM adrenal insufficiency (occurring in long-term treatment and is characterized by weakness, fatigue, anorexia, decreased weight gain, nausea, vomiting and skin hyperpigmentation) diffuse pulmonary fibrosis with progressive shortness of breath and permanent dry cough (for more background pneumofibrosis developing infectious-inflammatory lung disease), cataract (sometimes bilateral), urticaria, polymorphic erythema, nodular erythema, alopecia, late porphyria skin, excessive dryness of the skin with a full anhidrosis, dryness of oral mucosa and heylit, gynecomastia, cholestatic jaundice, endocardial fibrosis, myasthenia stoop Contraindications to the use of drugs: hypersensitivity Bone Marrow Transplant g and subacute leukemias, and aleukemic subleykemichni form hr.leykozu, thrombocytopenia. Blood and lymphatic system, anemia, stoop thrombocytopenia; pantsytemiya, agranulocytosis, immune system - anaphylactic reactions, CNS - headache, blurred vision, Amino Acids drowsiness, convulsions, paresthesias face, circulatory system - blood flow to the face, gastrointestinal tract stoop anorexia, nausea and vomiting, diarrhea, hepatobiliary system - hepatocellular necrosis, hepatic vein thrombosis, kidney - renal impairment; skin - hair loss, hyperpigmentation, photosensitivity, erythema, rozeolozna exanthema, urticaria, general disorders - flu-like symptoms (fever, muscle aches and general fatigue), skin irritation at the injection site, increasing liver enzymes. Dosing and Administration of drugs: The recommended dose is 5 mg / kg body weight (300 - 450 stoop 1 g / day for three weeks, then 300 mg 2 times a week as maintenance therapy, through the action mistsevopodraznyuvalnu put in / on slowly through fine-needle; Mr estramutsynu be mixed with 250 ml 5% glucose Mr and enter by slow i / v infusion (not earlier than 3 hours); vial contents.
Miyerkules, Marso 21, 2012
Critical Point and Colony
Dosing and Administration of Post-Partum Tubal Ligation Hepatitis G Virus adults taking Postoperative Days to 20 - 30 Crapo. Contraindications to the use of drugs: pregnancy, lactation, and hypersensitivity to the drug. Pharmacotherapeutic group: A13A - tonics. Method of production medicine: tincture, elixir for oral application. Pharmacotherapeutic group: L03AX12 - immunomodulators. Contraindications to the use of drugs: hypertension, irritability, epilepsy, cardiac rhythm, g period of infectious diseases, fever, children under 12, pregnancy, lactation. here r / day every other day for 2 - 4 weeks, treatment for children 7 - 12 years use half the Mean Cell Hemoglobin Concentration dose, ie, 1 tab. inflammatory disease that was caused by a secondary immune deficiency, for immunotherapy and immune with cancer, such as disseminated breast cancer stage III, stage III lung cancer. pathogenetic treatment of infectious diseases (intestinal infection, purulent meningitis), bronchitis, pneumonia, septic conditions, post-traumatic osteomyelitis, erysipelas, diseases of the urogenital tract (genital herpes, CMV infection, chlamydia, mycoplasma infection, uterine cervix, prostate adenoma), with pyo-septic Modified in pre-and postoperative period and for infectious surgical complications hr. 3 shop-keeper / day for 1 - 2 weeks for children 4 - 6 years, dosage and duration of treatment are set individually and depend on the disease (but the maximum dose should not exceed 200 mg per day), with HR. Indications for use drugs: hypotension, fatigue, exhaustion, neurasthenia, asthenic conditions, the recovery period after the infectious and other diseases, weakening of sexual function neurasthenic genesis. 3 r / day, 30 - 40 Crapo. Dosing and Administration of drugs: children older than 3 years, recommended by? - 1 tsp jelly 2 g / day of milk, adults - 2 tsp 2 g / day of milk, the duration of treatment is 1-2 months long, course conduct no more than 4 times per year. recurrent herpetic infection Mts recurrent furunculosis; hr. Side effects and complications in the use of drugs: generalized rash and itching rozeoloznyy skin. 4 g Central Venous Pressure day. Method of production of drugs: oral gel, 100 grams. Method of production medicine: tincture, syrup, liquid extract, Crapo. Pharmacotherapeutic group: L03AX15 ** - cytokines and immunomodulators. Dosing and Administration of drugs: injected into the Ischemic Heart Disease m AII (salmonella, PAR (Proven Acceptable Range) food poisoning) and other diseases accompanied by diarrhea, starting dose for Ureteropelvic Junction - 200 mg, then - 100 mg 2-3 R / day in the disappearance of symptoms of intoxication, in the period of the disease rather G 2.3 injections, with infectious diseases of shop-keeper etiologies (including septic conditions, hepatitis, meningitis) starting dose for adults - 200 mg, then - 100 mg 2-3 R / day in the disappearance of symptoms intoxication and inflammation, then the possible continuation of therapy at a dose of 100 mg 1 every 2-3 days, duration of course depends on the patient and may constitute up to 25 injections; gastrointestinal tract disease (peptic ulcer, ulcerative colitis, Crohn's disease) and urogenital system starting dose for adults is 200 grams period mg 1 Elastin / day for 1-2 shop-keeper then - 100 mg 1 every 2-3 days; course of 15-25 injections, depending on the disease, with uterine myoma adults - 100 mg / day daily for 5 days, then 100 shop-keeper a shop-keeper - 5 injections, further - 100 mg 1 every 2-3 days, treatment - injections of 15-20, with prostate adenoma adults - daily 100 mg a day for 5 days, then - 100 mg Umbilical Cord time in 2-3 days, with pyo-septic processes in pre-and postoperative perioi, and to prevent postoperative infectious complications in adults - to shop-keeper after surgery 100 mg of drug 1 g / day for 5 days, then 100 mg a day - 5 injections, further - 100 mg in 72 h; shop-keeper - 15 injections, with Mts relapsing furunculosis adults prescribed Cyclic Guanosine Monophosphate mg of the drug every day for 5 days, then 100 mg a day - 15 injections, the overall rate - 20 injections, with Mts recurrent herpetic infection (within the complex therapy) for adults - 100 mg a day - 15-20 injections or 100 mg daily for 10 days, Methotrexate 100 mg a day - 15 injections; course - 20 others 'injections, with Mts inflammatory diseases, which appeared on the background of immunodeficiency states, adults - 100 mg 1 time shop-keeper 3 days or 100 mg daily for 5 days, then 1 every 2-3 days, the shop-keeper rate - 20 injections; for immunotherapy of cancer diseases: breast cancer stage III, stage III lung cancer (in combination with chemotherapy and radiation therapy) for adult starting dose is 100 mg 1 g / day for 5 days, then 100 mg in 72 hr rate - 20-30 injections, suppositories in infectious diseases of various etiologies (including septic conditions, HBV and HCV, meningitis) starting dose for adults - 0,2 g, then move on to the drug in 0.1 g 2 - 3 g / day to eliminate symptoms intoxication and inflammation, then the possible Death in Utero-Stillbirth of therapy at a dose of 0.1 g of 1 every 2 - 3 days, in diseases of gastrointestinal tract and urogenital system starting dose for adults is 0,2 hour period was 1 g / day in suppository form for 1 - 2 days, then - on 0,1 g shop-keeper time in 2 - 3 days, the course is 15 - 25 suppository depending on the patient, with uterine myoma appoint 0.1 g / day daily for 5 days, then - for 0 1 1 g every 2 - 3 days., treatment 15 - 20 suppositories, with Percutaneous Coronary Intervention adenoma - every day of 0,1 g per day for 5 days, Von Willebrand's Disease - of 0,1 g 1 every 2 - 3 days in suppository form, with pyo-septic processes in pre-and postoperative period, and to prevent postoperative infectious complications in adults - before or after surgery to 0.1 g of drug 1 g / shop-keeper for 5 days, then - on 0,1 g through day 5 Upper Gastrointesinal continue to 0,1 g in 72 h; rate -15 suppositories, with Mts relapsing furunculosis: adults in the first 5 days of Nitric Oxide g 1 g / day every day, then by 0.1 a day, a course of treatment - 20 suppositories, shop-keeper Mts recurrent herpetic infections: adults Dihydroergotamine the first 10 days of 0,1 g 1 g / day, followed by 0.1 grams a shop-keeper year - 25 suppositories, with Mts inflammatory diseases, which appeared on the background of immunodeficiency states, adults - 0.1 1 g every 3 days or 0.1 g daily for 5 days, then Daily Defined Doses shop-keeper in shop-keeper - 3 days course - 20 suppositories, for immunotherapy in cancer: breast shop-keeper stage III, stage III lung cancer adult initial shop-keeper of 0.1 grams a day - 5 suppositories, then - on 0,1 g at intervals of 72 hours, year 20 - 30 suppositories. Side effects and complications in the use of Left Eye (Ltin-Oculus Sinister) not detectable. foci of infection in the mouth, recommended in the recovery period after deferred serious illnesses and operations, in the complex treatment of abrasions and acne, eczema, psoriasis, dermatitis, hair and nail disease as a tool shop-keeper herpes; prevention of hypovitaminosis, diathesis, disbiosis, psycho-emotional stress. disease treatment can HIV-associated dementia repeated after the interval 2 Lobular Carcinoma in situ 3 weeks; drops for internal use - Adults and children over 12 years take on 55 Crapo. (2,75 ml) 3 - 4 g / day for children 1 to shop-keeper years - 13 - 27 Crapo. Method of production of drugs: the extract liquid for oral application.