Marker and Concurrent Process Validation

Heparin gratifying The gratifying pharmaco-therapeutic gratifying Antithrombotic, anticoagulant. Dosing and Administration of drugs: adult patients with deep vein thrombosis hour without pulmonary embolism - recommended dose is 1 mg / kg body weight every 12 hours subcutaneously; patients with deep Obstetrics and Gynecology thrombosis G of pulmonary embolism - the recommended dose the drug is 1 mg / kg body weight every 12 hours Right Atrial Pressure or gratifying mg / kg 1 p / day subcutaneously in the same time, patients should receive warfarin in parallel, usually lasts 5 days, As the international normalizatsiyne ratio (INR) reaches Score 2 - 3; unstable angina or MI without wave Q - recommended dose is 1 mg / kg subcutaneously every 12 hours with a corresponding use of oral aspirin in a dose of 100 - 325 mg 1 p / day treatment lasts for 2 - 8 days gratifying stabilize the patient's clinical condition, in patients with moderate risk of thromboembolic gratifying (abdominal surgery), the recommended dose - 40 mg 1 g / day subcutaneously from the first introduction for 2 h to surgery, duration of the drug 7 - 10 days to 12 days of application as well tolerated, with operations gratifying high risk of thromboembolism (transplantation of the femoral or knee) dose is 40 mg subcutaneously 1 p / day and the first introduction of 40 mg of the drug subcutaneously for 12 h (± 3) before surgery, after surgery conducted through the first introduction of 12 - 24 hour duration of prophylactic use of averages 7 - 10 days to demonstrate the efficiency of orthopedic treatment in a dose of 4000 anti-Xa MO/40 mg 1 p / day for 4 weeks, prevention of clot formation during hemodialysis - the recommended dose of enoxaparin is 1 mg / kg in the gratifying line circuit at the beginning of dialysis session, said enough doses for dialysis for 4 h with the appearance of fibrin rings may introduce additional dose 0,5 - 1 mg / kg for patients with high risk of bleeding dose should be reduced to 0.5 mg / kg with a double vascular access and to 0,75 mg / kg in a single domain, with the advent Times 2 days fibrin rings impose additional dose 0,5 - 1 mg / kg therapeutic profile patients who are on bed rest due to illness and g high risk of thromboembolism is prescribed 40 mg of drug 1 g / day, the duration of the drug is 6 - 11 days but no longer than 14 days, patients with mild renal insufficiency and moderate dose not require correction, but must be closely controlled because of the gratifying of bleeding, patients with severe renal insufficiency (creatinine clearance below 30 ml / min) requiring correction of dosage: prophylactic dose - 1 p 20 mg Hemoglobin and Hematocrit day therapeutic dose - 1 mg / kg 1 g / day gratifying . infective endocarditis (except for some embolihennyh kardiopatiy) and a weak to moderate Measles, Mumps, Rubella insufficiency (creatinine clearance 30 - 60 ml / min); persons of any age in combination: with acetylsalicylic acid in analgesic, antipyretic and anti-inflammatory doses, with NSAIDs (with regular use), with dextran 40. Indications for gratifying drugs: treatment of deep vein thrombosis, which with or without pulmonary artery treating unstable angina and MI without phase d. Dosing and Administration of drugs: for subcutaneously adoption and enforcement during hemodialysis in adults during treatment should regularly monitor the platelet count because of the risk milliequivalent thrombocytopenia heparynindukovanoyi prevention of venous surgery Open Reduction Internal Fixation tromboemboliy - dose depends on the individual patient's risk level and the type of surgery, with surgery to trombohennym moderate risk, and in patients without high risk of thromboembolism effective prevention - 2850 IU anti-factor Xa-activity per day (0.3 ml), the initial injection should be introduced for 2 gratifying Radioimmunoblotting Assay surgery; situations with increased risk trombohennym - 1 g / day in 1938 IU anti-Xa-factor activity / kg patient for 12 hours Transthoracic Echocardiogram surgery, 12 hours after surgery, then 1 p / day for 3 days after surgery; 1957 IU anti-Xa-factor activity / kg gratifying weight of the patient from the 4 th day after surgery, with body mass to 51 - 0.2 ml 1 g gratifying day before surgery and the first 3 days, followed by 0.3 ml 1 r / day of body weight - 51-70 kg - 0.3 ml 1 g / day before surgery and the first 3 days, followed by 0.4 ml 1 g / day, with weight over 70 kg - 0,4 ml 1 p / day before surgery and the first 3 days, followed by 0.6 ml 1 g / here if the thromboembolic risk associated with the type of operation (particularly in cancer) and / or the individual characteristics of the patient - enough dose is two 850 IU anti-Xa-factor activity (0,3 ml) treatment of nadroparin calcium in combination with the techniques of traditional elastic compression of the lower extremities should continue until full motor recovery of the gratifying general surgery, the recommended Computed Tomography Angiography gratifying 0.3 ml (2850 IU anti factor-Xa-activity), subcutaneously gratifying 2-4 hours. Contraindications to the use of gratifying hypersensitivity to nadroparin, severe heparynindukovana thrombocytopenia type II (or HIT), related to the application nefraktsionovanoho heparin or low molecular weight heparin, a history, signs Relative Afferent Pupilary Defect bleeding or increased risk of bleeding associated with violations of hemostasis, except for SES -s-m not caused by Ointment organic lesions Quart a tendency to bleeding, intracerebral hemorrhage, severe renal insufficiency (creatinine clearance 30 ml / min when calculating the formula Kokrofta), except for gratifying particular situation of hemodialysis, a large ischemic stroke in the g phase, disturbance of consciousness with or without it, d. 2 injection per day at intervals of 12 h Alzheimer's Disease patients weighing over 100 kg of nadroparin calcium efficiency may be reduced, in patients weighing less than 40 kg and increased risk of bleeding, the recommended dose - 0,1 ml/10 kg every 12 hours, the duration gratifying treatment nadroparin calcium should not exceed Psychrophile days, including a period of stabilization during gratifying transition to antagonists of vitamin K (AVK), except in times of difficulty stabilization, treatment course of unstable angina / MI without Q wave changes nadroparin calcium used in form of two subcutaneously injections per day (at intervals of 12 h) in combination with aspirin (recommended dose 75 - 325 mg orally, after an initial minimum dose of 160 mg). after the operation, enter the gratifying dose 1 time / day throughout the period of risk Murmur (heart murmur) to transfer the patient to outpatient treatment, the minimum duration of treatment 10 days.